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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: O00299




USC-OGP 2-DE database:  O00299


O00299


General information about the entry
View entry in simple text format
Entry nameCLIC1_HUMAN
Primary accession numberO00299
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Chloride intracellular channel protein 1; AltName: Full=Chloride channel ABP; AltName: Full=Nuclear chloride ion channel 27; Short=NCC27; AltName: Full=Regulatory nuclear chloride ion channel protein; Short=hRNCC;.
Gene nameName=CLIC1
Synonyms=G6, NCC27
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-7 {PLATELET 4-7}
Homo sapiens (Human)
PLATELET_4-7
  map experimental info
 
PLATELET_4-7

MAP LOCATIONS:
pI=5.05; Mw=30592
pI=5.09; Mw=30517



PLATELET_5-6 {PLATELET 5-6}
Homo sapiens (Human)
PLATELET_5-6
  map experimental info
 
PLATELET_5-6

MAP LOCATIONS:
pI=5.07; Mw=31444
pI=5.10; Mw=30293

Cross-references
UniProtKB/Swiss-ProtO00299; CLIC1_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameCLIC1_HUMAN
Primary accession numberO00299
Secondary accession number(s) Q15089 Q502X1
Sequence was last modified on January 23, 2007 (version 4)
Annotations were last modified on March 15, 2017 (version 184)
Name and origin of the protein
DescriptionRecName: Full=Chloride intracellular channel protein 1; AltName: Full=Chloride channel ABP; AltName: Full=Nuclear chloride ion channel 27; Short=NCC27; AltName: Full=Regulatory nuclear chloride ion channel protein; Short=hRNCC;
Gene nameName=CLIC1
Synonyms=G6, NCC27
Encoded onName=CLIC1; Synonyms=G6, NCC27
Keywords3D-structure; Acetylation; Cell membrane; Chloride; Chloride channel; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Glutathionylation; Ion channel; Ion transport; Membrane; Nucleus; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport; Voltage-gated channel.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU93205; AAC25675.1; -; mRNA
EMBLAF034607; AAD20437.1; -; mRNA
EMBLAF109197; AAD26137.1; -; mRNA
EMBLAJ012008; CAB46078.1; -; Genomic_DNA
EMBLCR542071; CAG46868.1; -; mRNA
EMBLAF129756; AAD18073.1; -; Genomic_DNA
EMBLBA000025; BAB63376.1; -; Genomic_DNA
EMBLAL662899; CAI18417.1; -; Genomic_DNA
EMBLBC064527; AAH64527.1; -; mRNA
EMBLBC095469; AAH95469.1; -; mRNA
EMBLX87689; CAA61020.1; -; mRNA
CCDSCCDS4719.1; -; .
RefSeqNP_001274522.1; NM_001287593.1; .
RefSeqNP_001274523.1; NM_001287594.1; .
RefSeqNP_001279.2; NM_001288.4; .
UniGeneHs.414565; -; .
PDB1K0M; X-ray; 1.40 A; A/B=1-241
PDB1K0N; X-ray; 1.80 A; A/B=1-241
PDB1K0O; X-ray; 1.75 A; A/B=1-241
PDB1RK4; X-ray; 1.79 A; A/B=1-241
PDB3O3T; X-ray; 1.70 A; A=1-241
PDB3P8W; X-ray; 2.00 A; A=1-241
PDB3P90; X-ray; 2.30 A; A=1-241
PDB3QR6; X-ray; 1.78 A; A=1-241
PDB3SWL; X-ray; 2.35 A; A=6-241
PDB3TGZ; X-ray; 2.30 A; A/B=1-241
PDB3UVH; X-ray; 1.84 A; A/B=1-241
PDB4IQA; X-ray; 2.49 A; A/B=6-241
PDB4JZQ; X-ray; 1.35 A; A/B=1-241
PDB4K0G; X-ray; 1.40 A; A=2-241
PDB4K0N; X-ray; 1.25 A; A=1-241
PDBsum1K0M; -; .
PDBsum1K0N; -; .
PDBsum1K0O; -; .
PDBsum1RK4; -; .
PDBsum3O3T; -; .
PDBsum3P8W; -; .
PDBsum3P90; -; .
PDBsum3QR6; -; .
PDBsum3SWL; -; .
PDBsum3TGZ; -; .
PDBsum3UVH; -; .
PDBsum4IQA; -; .
PDBsum4JZQ; -; .
PDBsum4K0G; -; .
PDBsum4K0N; -; .
ProteinModelPortalO00299; -; .
SMRO00299; -; .
BioGrid107604; 57; .
IntActO00299; 42; .
MINTMINT-1033423; -; .
STRING9606.ENSP00000364934; -; .
TCDB1.A.12.1.2; the intracellular chloride channel (clic) family; .
iPTMnetO00299; -; .
PhosphoSitePlusO00299; -; .
SwissPalmO00299; -; .
BioMutaCLIC1; -; .
OGPO00299; -; .
SWISS-2DPAGEO00299; -; .
EPDO00299; -; .
PaxDbO00299; -; .
PeptideAtlasO00299; -; .
PRIDEO00299; -; .
TopDownProteomicsO00299; -; .
DNASU1192; -; .
EnsemblENST00000375779; ENSP00000364934; ENSG00000213719; .
EnsemblENST00000375780; ENSP00000364935; ENSG00000213719; .
EnsemblENST00000375784; ENSP00000364940; ENSG00000213719; .
EnsemblENST00000383404; ENSP00000372896; ENSG00000206394; .
EnsemblENST00000383405; ENSP00000372897; ENSG00000206394; .
EnsemblENST00000395892; ENSP00000379229; ENSG00000213719; .
EnsemblENST00000400052; ENSP00000382926; ENSG00000206394; .
EnsemblENST00000400058; ENSP00000382931; ENSG00000206394; .
EnsemblENST00000415179; ENSP00000409247; ENSG00000226248; .
EnsemblENST00000418285; ENSP00000407791; ENSG00000226417; .
EnsemblENST00000420458; ENSP00000410965; ENSG00000226651; .
EnsemblENST00000422167; ENSP00000407429; ENSG00000226248; .
EnsemblENST00000423055; ENSP00000406968; ENSG00000226417; .
EnsemblENST00000423143; ENSP00000404589; ENSG00000223639; .
EnsemblENST00000423804; ENSP00000409979; ENSG00000230685; .
EnsemblENST00000425464; ENSP00000401292; ENSG00000223639; .
EnsemblENST00000431921; ENSP00000408357; ENSG00000226248; .
EnsemblENST00000433916; ENSP00000391395; ENSG00000226651; .
EnsemblENST00000434202; ENSP00000400532; ENSG00000226651; .
EnsemblENST00000435242; ENSP00000412217; ENSG00000226417; .
EnsemblENST00000438708; ENSP00000406088; ENSG00000226248; .
EnsemblENST00000438750; ENSP00000404037; ENSG00000223639; .
EnsemblENST00000442045; ENSP00000400280; ENSG00000226417; .
EnsemblENST00000447338; ENSP00000413330; ENSG00000230685; .
EnsemblENST00000447369; ENSP00000408094; ENSG00000230685; .
EnsemblENST00000451546; ENSP00000416211; ENSG00000223639; .
EnsemblENST00000456863; ENSP00000406335; ENSG00000226651; .
EnsemblENST00000457485; ENSP00000398056; ENSG00000230685; .
EnsemblENST00000614673; ENSP00000480256; ENSG00000230685; .
EnsemblENST00000614982; ENSP00000477623; ENSG00000206394; .
EnsemblENST00000616760; ENSP00000479808; ENSG00000213719; .
EnsemblENST00000618288; ENSP00000479501; ENSG00000226417; .
EnsemblENST00000619727; ENSP00000482255; ENSG00000226651; .
EnsemblENST00000621055; ENSP00000478930; ENSG00000226248; .
EnsemblENST00000622613; ENSP00000484581; ENSG00000223639; .
GeneID1192; -; .
KEGGhsa:1192; -; .
CTD1192; -; .
DisGeNET1192; -; .
GeneCardsCLIC1; -; .
HGNCHGNC:2062; CLIC1; .
HPACAB020825; -; .
HPACAB040557; -; .
MIM602872; gene; .
neXtProtNX_O00299; -; .
OpenTargetsENSG00000213719; -; .
PharmGKBPA26588; -; .
eggNOGENOG410INGZ; Eukaryota; .
eggNOGENOG410ZZZX; LUCA; .
GeneTreeENSGT00550000074477; -; .
HOGENOMHOG000231548; -; .
HOVERGENHBG050994; -; .
InParanoidO00299; -; .
KOK05021; -; .
OMAVCLKYRS; -; .
OrthoDBEOG091G0IHT; -; .
PhylomeDBO00299; -; .
TreeFamTF315438; -; .
SignaLinkO00299; -; .
ChiTaRSCLIC1; human; .
EvolutionaryTraceO00299; -; .
GeneWikiCLIC1; -; .
GenomeRNAi1192; -; .
PROPR:O00299; -; .
ProteomesUP000005640; Chromosome 6; .
BgeeENSG00000206394; -; .
CleanExHS_CLIC1; -; .
ExpressionAtlasO00299; baseline and differential; .
GenevisibleO00299; HS; .
GOGO:0072562; C:blood microparticle; IDA:UniProtKB; .
GOGO:0005903; C:brush border; TAS:UniProtKB; .
GOGO:0034707; C:chloride channel complex; IEA:UniProtKB-KW; .
GOGO:0005737; C:cytoplasm; IDA:UniProtKB; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0005615; C:extracellular space; IDA:UniProtKB; .
GOGO:0016020; C:membrane; IDA:UniProtKB; .
GOGO:0005739; C:mitochondrion; IEA:Ensembl; .
GOGO:0005635; C:nuclear envelope; IDA:MGI; .
GOGO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL; .
GOGO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0031982; C:vesicle; IDA:UniProtKB; .
GOGO:0045296; F:cadherin binding; IDA:BHF-UCL; .
GOGO:0005254; F:chloride channel activity; IDA:MGI; .
GOGO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW; .
GOGO:0006821; P:chloride transport; IDA:MGI; .
GOGO:0070527; P:platelet aggregation; IMP:UniProtKB; .
GOGO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl; .
GOGO:0051726; P:regulation of cell cycle; IEA:InterPro; .
GOGO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl; .
GOGO:0007165; P:signal transduction; TAS:UniProtKB; .
Gene3D1.20.1050.10; -; 1; .
Gene3D3.40.30.10; -; 1; .
InterProIPR002946; CLIC; .
InterProIPR030259; CLIC-1; .
InterProIPR010987; Glutathione-S-Trfase_C-like; .
InterProIPR004045; Glutathione_S-Trfase_N; .
InterProIPR012336; Thioredoxin-like_fold; .
PANTHERPTHR11260:SF473; PTHR11260:SF473; 1; .
PfamPF13409; GST_N_2; 1; .
PRINTSPR01263; INTCLCHANNEL; .
SFLDSFLDG01175; Main.10_; 1; .
SUPFAMSSF47616; SSF47616; 1; .
SUPFAMSSF52833; SSF52833; 1; .
TIGRFAMsTIGR00862; O-ClC; 1; .
PROSITEPS50405; GST_CTER; 1; .



USC-OGP 2-DE database image


Gateways to other related servers


Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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